Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the treatment method of many myeloma. Its synthesis or analyze is important for making certain the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the therapy of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A essential compound while in the synthesis of imatinib, a drug that targets particular types of most cancers, which includes chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are definitely intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their study is crucial for optimizing the manufacturing method and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is applied to treat breast cancer, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is 4S)-3-Hydroxy-4-phenyl-2-azetidinone an estrogen receptor antagonist Employed in the treatment of breast cancer. Many intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in treating cancers which include ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is linked to the synthesis of adamantane derivatives, that have a variety of purposes, which includes antiviral Houses.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for style two TBTU diabetes that inhibits the enzyme DPP-four to regulate blood sugar stages.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of assorted gluconic acid derivatives, which can be Employed in food items, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor during the synthesis of canagliflozin, a medication used to handle variety two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).